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Data Sciences International finepointe software
Finepointe Software, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/finepoint+software/finepointe+software/pm42025021-152-7-9
Average 86 stars, based on 1 article reviews
finepointe software - by Bioz Stars, 2026-10
86/100 stars

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Software:

Article Title: Development, characterization and standardization of a nose-only inhalation exposure system for exposure of rabbits to small particle aerosols containing Francisella tularensis
Article Snippet: .. This has already been demonstrated for NHP using the same Biaera AeroMP system that we use , and we are currently evaluating a new version of the Finepoint software (Data Sciences International, St. Paul, MN) that would do the same for rabbits. ..

Article Title: Multi-dimensional evaluation of cardiotoxicity in mice following respiratory exposure to polystyrene nanoplastics.
Article Snippet: .. Before exposure, Finepoint software (Data Sciences International [DSI] St. Paul, MN) was used to detect the respiratory rate of mice. ..

Article Title: Col4a3 -/- Mice on Balb/C Background Have Less Severe Cardiorespiratory Phenotype and SGLT2 Over-Expression Compared to 129x1/SvJ and C57Bl/6 Backgrounds
Article Snippet: .. Respiratory function was monitored unrestrained in conscious mice by the Buxco small animal whole-body plethysmography system and FinePoint software (Data Science International, New Brighton, MN, USA). ..

Article Title: Mouse Model of Heart Failure With Preserved Ejection Fraction Driven by Hyperlipidemia and Enhanced Cardiac Low‐Density Lipoprotein Receptor Expression
Article Snippet: .. Respiratory function was assessed using a Buxco small animal whole body plethysmography system and FinePoint software (Data Science International, New Brighton, MN). ..

Article Title: Growth hormone-releasing hormone receptor antagonist MIA-602 attenuates cardiopulmonary injury induced by BSL-2 rVSV-SARS-CoV-2 in hACE2 mice.
Article Snippet: .. Respiratory function was monitored unrestrained in conscious mice by the Buxco small animal whole- body plethysmography system and FinePoint software (Data Science International). ..

Article Title: Growth hormone–releasing hormone receptor antagonist MIA-602 attenuates cardiopulmonary injury induced by BSL-2 rVSV-SARS-CoV-2 in hACE2 mice
Article Snippet: .. Respiratory function was monitored unrestrained in conscious mice by the Buxco small animal whole-body plethysmography system and FinePoint software (Data Science International). ..

Article Title: Gene network analysis for identification of microRNA biomarkers for asthma
Article Snippet: .. Mice were mechanically ventilated and lung airway resistance and compliance were measured in response to increasing doses (0–12.5 mg/ml in PBS) of aerosolized methacholine using Buxco equipment and FinePoint software from Data Sciences International (St. Paul, MN). ..

Article Title: The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALS
Article Snippet: .. The chamber was calibrated before every experiment, selecting the most appropriate response observed in FinePoint Software (Buxco, Data Sciences International) to the injection of 1 ml of air into the chamber. ..

Mouse Assay:

Article Title: Gene network analysis for identification of microRNA biomarkers for asthma
Article Snippet: .. Mice were mechanically ventilated and lung airway resistance and compliance were measured in response to increasing doses (0–12.5 mg/ml in PBS) of aerosolized methacholine using Buxco equipment and FinePoint software from Data Sciences International (St. Paul, MN). ..

Injection:

Article Title: The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALS
Article Snippet: .. The chamber was calibrated before every experiment, selecting the most appropriate response observed in FinePoint Software (Buxco, Data Sciences International) to the injection of 1 ml of air into the chamber. ..



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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography (WBP) measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.

Journal: bioRxiv

Article Title: Sex-Specific Pathophysiological Signatures in Allometric Dosing-Controlled Bleomycin Acute Lung Injury Model

doi: 10.64898/2026.03.10.710851

Figure Lengend Snippet: ( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography (WBP) measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.

Article Snippet: Data was recorded using DSI FinePointe WBP software (Data Sciences International, St. Paul, MN, USA).

Techniques: